Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. In the first group, some people continued taking iron by mouth, while other people took Injectafer. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. You may report side effects to FDA at 1-800-FDA-1088. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. What to Know About Iron Infusions for Anemia Treatment - GoodRx However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Does Venofer Vial interact with other medications? Use of the term female in this article refers to sex assigned at birth. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Throw away unused or expired drugs. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. This gives a total cumulative dose of 1,500 mg of Injectafer. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). (A generic drug is an exact copy of the active drug in a brand-name medication.) The infusion will take between 15-30 minutes if it is given in. Its possible to get rid of or reduce the severity ofside effects. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. * Feraheme has a boxed warning for this side effect. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. With IDA, you have low hemoglobin levels. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. The drug helps increase your hemoglobin level back to a value thats within the normal range. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. People from different ethnic backgrounds process medications differently. The drug helps increase your hemoglobin level back to a value thats within the normal range. You may report side effects to Health Canada at 1-866-234-2345. Other drugs are available that can treat iron deficiency anemia (IDA). Here we look at how Injectafer and Venofer are alike and different. Feeling awful 10 days after Iron Infusion. Is it normal? Data on file, American Regent, Inc. 1. The study also didnt show if one treatment was worse than the other. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Ask your doctor or healthcare provider if Venofer is the right choice for you. How long does iron infusion stay in your system? Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Tell all of your health care providers that you take Venofer. (For more information on Venofer, see the Injectafer vs. Venofer section above). Iron infusion side effects vary depending on which form is being used. Version: 7.01. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Theseside effectscan range from being mild tosevere. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Common and Rare Side Effects for Venofer Vial - WebMD (A medication class describes a group of drugs that work in the same way.). If you notice other effects not listed above, contact your doctor or pharmacist. Yes, in some cases it may. Patients with celiac disease (gluten intolerance). Call your doctor for medical advice about side effects. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Your doctor will be able to see how Venofer is working by reviewing your blood tests. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. VenAccess is a trademark of Vifor (International) Inc. Switzerland. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. This website is intended for use by US patients. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. Their medical staff can help you set up another time to receive your Injectafer dose. There are currently no generic forms of either drug. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Then the study was split into the following two groups, which are discussed below. This is not a complete list of side effects and others may occur. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. You may report side effects to the FDA at 1-800-332-1088. Venofer (iron sucrose): Anemia Medication Uses & Side Effects - MedicineNet Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. I hope you found answers and are feeling better now. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. iron sucrose (injection) Uses, Side Effects, Dosage & Interactions The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. This survey is being conducted by the WebMD marketing sciences department. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. This means you would get two Injectafer doses of 720 mg each. Injectafer begins working as soon as it enters your body. Innovators Monograph So theres no recommended pediatric dosage for Injectafer. Health careproviderscan provide information on how longside effectslast by checking amedication guide. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes Consult your pharmacist or local waste disposal company. stream Injectafer comes as a liquid solution inside vials. Venofer: Uses, Price, Dosage, Side Effects, Substitute, Buy Online Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Change in taste. You may also need to monitor your blood pressure at home. Learn about the causes, symptoms, diagnosis, and treatment of this. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. Talk with your doctor. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. But for other people, their IDA returns after treatment with Injectafer. Before using, check this product visually for particles or discoloration. This includes your doctors, nurses, pharmacists, and dentists. Follow all instructions closely. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Copyright 1996-2023 Cerner Multum, Inc. Venofer (Iron Sucrose (Injection)) - Side Effects, Interactions, Uses pain in the arms or legs. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. MNT is the registered trade mark of Healthline Media. Generics tend to cost less than brand-name drugs. Hes an expert in genetic testing, genetic analysis, andprecision medicine. However, consuming large amounts of alcohol can actually cause anemia in some people. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Venofer infusions- how long does it take to notice improvement?? - Reddit WebMD provides common contraindications for Venofer Vial. Its not known if Injectafer is safe to take during pregnancy. Tell your doctor about the allergy and what signs you had. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. And these two doses need to be separated by at least 7 days. Drug interactions may change how your medications work or increase your risk for serious side effects. All of the people took iron by mouth for 2 weeks. Its given by either intravenous (IV) infusion or slow IV injection. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ fever. This test measures the amount of hemoglobin in your blood. Things to remember when you fill your prescription. This is not a complete list of possible side effects. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Severeside effectsmay end up causing a lot of disruption in a persons life. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. 2 0 obj What are the possible side effects of Venofer? | Nutritive Agent But for other people, doing so could lead to having too much iron in their body. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Its responsible for carrying oxygen throughout your body. Always review your medical history with the treatingphysician. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. In the US - Call your doctor for medical advice about side effects. Talk to your pharmacist for more details. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Venofer - Iron sucrose uses, dose and side effects - zeepedia.com This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you notice any changes to your normal blood pressure, call your doctor right away. With IV infusion, the drug is given as a slow drip into your vein over a period of time. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. There are 2 tests that your doctor will likely They can give you tips on how to deal with any side effects that may be bothersome. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Very bad and sometimes deadly allergic side effects have rarely happened. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Not all possible drug interactions are listed here. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Taking a higher dose than needed can often lead to adverse effects. And theyll recommend how soon after starting the drug you need to have this level checked. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. It is important to get each dose of this medication as scheduled. Do not start, stop, or change the dose of any drug without checking with your doctor. With anemia, you have a low level of red blood cells (RBCs) in your body. Allergic reactions typically occur the first time your body is exposed to a drug. Effectiveness of Injectafer compared with iron thats taken by mouth. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Do not flush down a toilet or pour down a drain unless you are told to do so. Do not exceed 1,500 mg of iron per dosing course. For people with certain medical implants, such as pacemakers, an MRI may pose an . Venofer Intravenous: Uses, Side Effects, Interactions, Pictures - WebMD IQVIA [NSP Audit from MAT November 2013 to November 2018]. An iron infusion is a way to increase the body's iron levels quickly. . These people may lose weight as their anemia improves because theyre more active. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Back pain. Its not known how common delayed allergic reaction might be in other people using Injectafer. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Heart failure: Could a low sodium diet sometimes do more harm than good? Its because everyones body is different. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. wAd**CgI%"nn{Oa[q{r5 Procedure Details Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Phosphorus is an electrolyte that your body needs in order to make energy. And this can affect how well those parts of your body are able to work. They can recommend if this is safe for you to do. This is not a list of all drugs or health problems that interact with this medicine. Read all information given to you. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Keep all medications away from children and pets. Common and Rare Side Effects for Venofer Vial - WebMD Hemoglobin is a protein thats found inside your red blood cells. 4 0 obj Terminal half-life ranges from 7 to 12 hours. A shortage of iron can cause health problems. And this person had gotten their first dose of the drug without having an allergic reaction. Side effects are uncomfortable reactions to medications or drugs. Keep all regular medical and laboratory appointments. Injectafer contains the active drug ferric carboxymaltose. (A class of medications describes a group of drugs that work in the same way.). <> To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). Once inside your body, ferric carboxymaltose releases iron into your system. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Here we look at how Injectafer and Feraheme are alike and different. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Storage Condition Store in a cool and dry place protected from light. With IDA, you have low hemoglobin levels. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. experience severe side effects, please seek medical attention right away and notify the ordering physician. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Serious side effects from Injectafer arent common, but they can occur. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. endobj (IV iron is absorbed by the body more rapidly than oral iron.) I had Venofer infusions, 2 rounds now in the span of three years. 5 0 obj Injectafer contains the active drug ferric carboxymaltose. Cancer patients who have anemia and are taking an ESA. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Wellbutrin: Side effects and how to manage them - Medical News Today Venofer may reduce the absorption of iron preparations taken by mouth. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Any long-term side effects/dangers from iron infusions? : r/Anemic - Reddit Evenbirth controlcan lead to severeside effectslike bloodclots. We cancelled my 5th because of the reaction. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Before taking Injectafer, talk with your doctor about your health history. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. The oral form of the drug, called sucroferric oxyhydroxide and used . Boxed warnings alert doctors and patients about drug effects that may be dangerous. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Infusion times range from less than 20 minutes to up to 4 hours. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. But its only approved for use in people with CKD who may or may not need dialysis. US residents can call their local poison control center at 1-800-222-1222. I had my first infusion of 1gm 10 days ago. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Theyll recommend how to manage your condition. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Keep out of reach of children. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Notify your healthcare provider of any irritation at the injection site. Iron infusion: Uses, benefits, and what to expect - Medical News Today Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Tell your doctor if you are pregnant or plan to become pregnant. Here are answers to some frequently asked questions about Injectafer. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer.